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謝絹珠

謝絹珠(June Hsieh Wu

職稱:教 授

研究室:分子遺傳研究室

最高學歷:博 士

學校/國家:美國德州農工大學微生物學博士

分機號碼

電子郵件帳號

研究室現有:

博士班研究生

碩士班研究生

研究方向及研究室特色
過去的研究著重於台灣族群脂肪蛋白基因的研究及其與心臟血管疾病的關係。本實驗室與臨床醫師合作,對國內多種的脂肪蛋白基因分析其類型、發生率、分佈率及與疾病之關係。因臺灣族群極少有這方面的資訊,故這些論文也為世界的人類學研究中心所收集,這種台灣族群的基因型可用以應用到世界人類遷徙途徑的研究。另外對基因附近重覆序列,鑑定其序列特性及與疾病可能的關聯。
脂肪蛋白的生理功能也是興趣之一,因有緣與醣類研究接觸,對於醣蛋白(大部分脂肪蛋白也是醣蛋白)的功能與醣類型息息相關,故亦投入時間瞭解醣類的特性及其研究方法,且參與其研究。故近期研究多著重於對一種脂肪蛋白(a)上的醣分子研究其結構,其與血管內皮細胞之作用,另外微生物感染與免疫介質的分泌也大大的影響血管內皮細胞的生理功能,是否導致脂肪的堆積於血管壁也是我們研究的主題。
近年的研究主題也著重在克雷白式肺炎桿菌 (Klebsiella pneumoniae) 的致病機轉。克雷白式肺炎桿菌是重要的院內感染細菌,雖屬伺機性細菌,但近年來其抗藥性及毒性均增加,能引起肝膿腫,尤其在糖尿病患者。我們研究其莢膜結構及其與細胞之間的病理作用。利用小白鼠研究細菌之入侵及細胞培養方式研究細菌感染時之細胞的信息傳遞。利用二維電泳及蛋白質序列分析找出感染前後細胞蛋白質或基因之表現有何不同,以了解其致病機轉。

Publications

  • YC Fu, JT Yang, HW Chen JH Wu* (2010) Effect of lipoprotein (a) on annexin A5 binding to cell membrane. Clinica Chemica Acta in press.
  • JH Wu, AM Wu, Z Yang, YY Chen, B Sngha, LP Chow, JY Lin (2010) Recognition intensities of submolecular structures mammalian glycol-structural units, ligand cluster and polyvalency in abrin-a-carbohydrate interactions. Biochimie 92:147-156.
  • AM Wu, JH Wu, JH Liu, YY Chen, B Singha, LP Chow, JY Lin (2009) Roles of mammalian structural units, ligand cluster and polyvalency in the Abrus precatorius agglutinin and glycoprotein recognition process Mol Immunol 46:3427-3437.
  • AM Wu, JH Wu, T Singh, B Singha, D Sudakevitz, N Gilboa-Garber (2009) Multivalent human blood group ABH and Lewis glycotopes are key recognition factors for a LFuc>Man binding lectin from phytopathogenic Ralstonia solanacearum. Biochimic et Biophysica Acta 1790:249-259.
  • Z. Yang, J.H. Wu, H.W. Kao, R Kannagi, A.M. Wu (2009) Expression of sialyl Lex, sialyl Lea, Lex and Ley glycotopes in secreted human ovarian cyst glycoproteins. Biochimie 91: 423-433.
  • AM Wu, JH Wu, Z Yang, T Singh, IJ Goldstein, N Sharon (2008) Defferential contributions of recognition factors of two plant lectins – Amaranthus caudatus lectin and Arachis hypogea agglutinin, reacting with Thomsen-Friedenreich disaccharide (Galb1–3 GalNAca1-Ser/Thr) (2008) Biochimie 90:1769-1780
  • Z. Yang, M.S. Tsai, J.H. Wu, A. Herp, A.M. Wu (2008) Defining the carbohydrate specificities of Erythrina corallodendron lectin (ECorL) as polyvalent Galb1-4GlcNAc (II)>monomeric II>monomeric Gal and GalNAc. Chang Gung Med J 31: 26-43.
  • J.H. Wu, A.M. Wu, C.G. Tsai, X.Y. Chang, T.S. Wu (2008) Contribution of fucose containing capsules in Klebsiella pneumoniae to bacterial virulence in mice. Exp Biol Med 233: 64-70.
  • Z. Yang, M.S. Tsai, J.H. Wu, A. Herp, A.M. Wu (2008) Defining the carbohydrate specificities of Erythrina corallodendron lectin (ECorL) as polyvalent Galb1-4GlcNAc (II)>monomeric II>monomeric Gal and GalNAc. Chang Gung Med J 31: 26-43.
  • K.L Chien, W.H. Fang, H.C. Wen, H.P. Lin, Y.L. Lin, S.W. Lin, J.H. Wu, J.T.Kao (2008) APOA1/C3/A5 haplotype and risk of hypertriglyceridemia in Taiwanese. Clinica Chimica Acta 390: 56-62.
  • J.T. Yang, C.N. Chang, J.H. Wu, C.Y. Chung. H.H. Weng, W.C. Cheng, T.H. Lee (2008) Cigarette smokingdecreases neurotrophin-3 expression in rat hippocampus after transient forebrain ischemia. Neurosci Res 60:431-438.
  • S.H. Maa, H.L. Lee, Y.C. Huang, J.H. Wu, T.S. Tsou, K. MacDonald, I. Abraham (2008). Incidence Density and Relative Risk of Nosocomial Infections in Taiwan’s Only Children’s Hospital, 1999-2003. Infection Control and Hospital Epidemiology, 29(8), 767-770.
  • L.J. Lai, X. Xiao, J.H. Wu* (2007) Inhibition of corneal neovascularization with endostatin delivered by adeno-associated viral (AAV) vector in a mouse corneal injury model. J biomed Sci 14: 313-322
  • A.M. Wu, J.H. Wu, M.S. Tsai, Z. Yang, N. Sharon, A. Herp (2007) Differential affinities of Erythrina cristagalli lectin (ECL) toward monosaccharides and polyvalent mammalian structural units. Glycoconj J 24: 591-604
  • T.H. Lee, J.T. Yanf, H. Kato, J.H. Wu (2006) Hypertension downregulates the expression of brain-derived heurotrophic factor in the ischemia-vulnerable hippocampal CA1 and cortical areas after carotid artery occlusion. Brain Res 1112: 31-38
  • T Singh, JH Wu, WJ Peumans, P Rouge, EJM Van Damme, AM Wu (2007) Recognition profile of Morus nigra agglutinin (Morniga G) expressed by monomeric ligands, simple clusters and mammalian polyvalent glycotopes. Mol Immunol 44:451-462.
  • A.M. Wu, R. Singh, J.H. Wu, M. Lensch, S Andre, H.J. Gavius (2006) Interaction profile of galectin-5 with free saccharides and mammalian glycoproteins: probing its fine specificity and the effect of naturally clustered ligand presentation. Glycobiol 16: 524-537
  • J.H. Wu, L.C. Hong, Y.Y. Tsai, H.W. Chen, W.X. Chen, T.S. Wu (2006) Mitogen-activated protein kinase (MAPK) signaling pathways in HepG2 cells infected with a virulent strain of Klebsiella pneumoniae. Cellular Microbiol 8: 1467-1474.
  • AM Wu, JH Wu, T Singh, JH Liu, MS Tsai, N Gilboa-Garber (2006) Interactions of the fucose-specific Pseumonas aeruginasa lectin, PA-IIL, with mammalian glycoconjugates bearing polyvalent Lewisa and ABH blood group glycotopes. Biochimie 88:1479-1492.
  • A.M. Wu, J.H. Wu, T. Singh, L.J. Lai, Z. Yang, A. Herp (2006) Recognition factors of Ricinus communis agglutinin 1 (RCA1). Mol Immunol 43: 1700-1715.

 

  • J.H. Wu, T. Singh. A. Herp, A.M. Wu. (2006) Carbohydrate recognition factors of the lectin domains present in the Ricinus communis toxic protein (ricin). Biochimie 88: 201-217.
  • T. Singh, J.H. Wu, W.J. Peumans, P. Rouge, E.J.M. Van Damme, R.A. Alvarez, A.M. Wu (2006) Carbohydrate specificity of an insecticidal lectin isolated from the leaves of Glechoma hederacea towards mammalian glycoconjugates. Biochem J. 393: 331-341.
  • J.H. Wu, C.G. Tsai (2005) Infectivity of hepatic strain Klebsiella pneumoniae in diabetic mice. Exp Biol Med 230: 757-761.
  • A.M. Wu, J.H. Wu, T. Singh, P.Y. Hwang, M.S. Tsai, A. Herp (2005) Lectinochemical studies on the binding properties of a toxic lectin (ricin) isolated from the seeds of Ticinus communis. Chang Gung Med J 28: 530-542.
  • C.N. Chang, J.T. Yang, T.H. Lee, W.C. Cheng, Y.H. Hsu, J.H. Wu* (2005) Dexamethasone enhances the upregulation of nerve growth factor mRNA expression in ischemic rat brain. J. Clin Neurosci 12: 680-684.
  • A.M. Wu, J.H. Wu, H.W. Kuo, A. Herp (2005) Further characterization of the binding properties of two monoclonal antibodies recognizing human Tn red blood cells. J Biomed Sci 12: 1-14.
  • J.T. Yang, T.H. Lee, H.H. Weng, C.N. Chang, W.C. Chen, W.C. Cheng, J.H. Wu* (2005) Dexamethasone enhances NT-3 expression in rat hippocampus after traumatic brain injury. Experimental Neurology 192: 437-443.
  • T. Singh, U. Chatterjee, J.H. Wu, B.P. Chatterjee, A.M. Wu (2005) Carbohydrate recognition factors of a Ta(Galb1→3GalNAca1→Ser/Thr) and Tn (GalNAca1→Ser/Thr) specific lectin isolated from the seeds of Artocarpus lakoocha. Glycobiology 15: 67-78.
  • T.H. Lee, J.T. Yang, H. Kato, J.H. Wu, S.T. Chen (2004) Expression of brain-derived neurotrophic factor immunoreactivity and mRNA in the hippocampal AC1 and cortical areas after chronic ishcnia in rats. J. Neuroscience Res 76: 705-712.
  • A.M. Wu, J.H. Wu, J.H. Liu, T. Singh, S André, H. Kaltner, H Gabius (2004) Effects of polyvalency of glycotopes and natural modifications of human blood group ABH/Lewis sugars at the Galb1-terminated core saccharides on the binding of domain-1 of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N). Biochimie 86: 317-326.
  • A.M. Wu, J.H. Wu, T. Singh, K.C. Chu, W.J. Peumans, P. Rouge, E.J.M. Vam Damme (2004) A novel lectin (Morniga M) from mulberry (Morus nigra) bark recognizes oligomannosyl residues in N-glycans. J. Biomed Sci. 11: 874-885.
  • A.M. Wu, J.H. Wu, T. Singh, J.H. Liu, A. Herp (2004) Lectinochemical studies on the affinity of Anguilla anguilla agglutinin for mammalian glycotopes Life Sciences 75: 1085-1103.
  • A.M. Wu, J.H. Wu, J.H. Liu, T. Singh (2004) Recognition profile of Bauhinia purpurea agglutinin (BPA) Life Sciences 74: 1763-1779.
  • J.H. Wu, I.N. Lee (2003) Studies of apolipoprotein (a) promoter from subjects with different plasma lipoprotein (a) concentrations. Clin Biochem 36: 241-246.
  • A.M. Wu, J.H.Wu, A. Herp, J.H. Liu (2003) Effect of polyvalencies of glycotopes on the binding of a lectin from the edible mushroom, Agaricus bisporus. Biochem J. 371: 311-320.
  • A.M. Wu, J.H. Wu, L.H. Lin, J.H. Liu (2003) Binding profile of Artocarpus intergrifolia agglutinin (Jacalin). Life Sciences 72: 2285-2302.
  • J.H. Wu, S.K. Lo, M.S. Wen, J.T. Kao (2002) Characterization of apolipoprotein E genetic variations in Taiwanese: Association with coronary heart disease and plasma lipid levels. Human Biology 74: 25 – 31.
  • J.T Yang, C.N Chang, T.H. Lee, J.C. Hsu, T.N. Lin, Y.H. Hsu, J.H. Wu* (2002) Effect of dexamethasone on the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs after forebrain ischemia in the rat. Critical Care Medicine 30: 913 – 918.
  • AM Wu, JH Wu, MS Tsai, JH Liu, S Andre, K Wasano, H Kaltner, HJ Gabius (2002) Fine specificity of domain-I of recombinant tandem-repeat-type galectin-4 from rat gastrointestinal tract (G4-N). Biochemical J 367: 653-664.
  • J.H. Wu, Y.T. Lee, H.C. Hsu, L.L. Hsieh (2001) Influence of CETP gene variation on plasma lipid levels and coronary heart disease: a survey in Taiwan. Atherosclerosis 159: 451-458.
  • A.M. Wu, J.H. Wu, M.S. Tsai, H.Kaltner, H.J. Gabius (2001) Carbohydrate specificity of a galectin from chicken liver (CG16). Biochem J 358: 529-538. (SCI)
  • J.T. Yang, C.N. Chang, T.H. Lee, T.N. Lin, J.C. Hsu, Y.H. Hsu, J.H. Wu* (2001) Hyperbaric oxygen treatment decreases post-ischemic neurotrophin-3 mRNA down- regulation in the rat hippocampus. NeuroReport 12:3589-3592.
  • A.M. Wu, J.H. Wu, A. Herp, L.P. Chow, J.Y. Lin (2001) Carbohydrate specificity of a toxic lectin, abrin A, from the seeds of Abrus precatorius (jequirity bean). Life Science 69: 2027- 2038.
  • A.M. Wu, J.H. Wu, M.S. Tsai, G.V. Hegde, S.R. Inamdar, B.M. Swamy, A. Herp (2001) Carbohydrate specificity of a lectin isolated from the fungus Sclerotium rolfsii. Life Science 69: 2039-2050.
  • J.H. Wu, Y.T. Lee, H.C. Hsu, L.L. Hsieh, M.S. Wen, M.S. Chern, D.Wu (2001) Further characterization of apolipoprotein B genetic variations in Taiwanese. Human Biology 73: 451-460
  • A.M. Wu, J.H. Wu, M.S. Tsai, A. Herp (2000) Carbohydrates specificities of an agglutinin isolated from Trichosanthes kirlowii. Life Sciences 66: 2571 - 2581.
  • J.H. Wu, J.T. Kao, M.S Wen, S.K. Lo (2000) DNA polymorphism at apolipoprotein A1-CIII loci in Taiwanese: correlation of plasma apoCIII with triglyceride level and body mass index. J Formos Med Assoc 99: 367-374.
  • A.M. Wu, J.H. Wu, Y.Y. Chen, M.S. Tsai, A. Herp (1999) Forssman pentasaccharide and polyvalent Galb1®4GleNAc as major ligands with affinity for Caragana arboreseens agglutinin. FEBS Letters 463:225-230.
  • Y.C. Huang, T.L. Lin, H.S. Leu, H.L. Peng, J.H. Wu, H.Y. Chang (1999) Outbreak of Candida parapsilosis fungemia in neonatal intensive care units: Clinical implications and genotyping analysis. Infection 27: 97-102.
  • J.T. Yang, C.N. Chang, H. Hsu, K.C. Wei, T.K. Lin, J.H. Wu* (1999) The increase in CSF NGF concentration is positively correlated with poor prognosis of postoperative hydrocephalic patients. Clin Biochem 32:673-675
  • A.M. Wu, J.H. Wu, Y.Y. Chen, S.C. Song, E.A. kabat (1999) Further characterization of the combining sites of Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin A4. Glycobiology 9:1161-1170.
  • J.H. Wu, R.P. Hsieh, M.S. Chen, M.S. Wen, C.H. Tseng (1999) Association of 1617 C→T genetic variation in exon 11 of human low-density lipoprotein receptor and plasma lipid concentration. Atherosclerosis 143:217-218.
  • Y. C. Huang, T.Y. Lin, H.L. Peng, J.H. Wu, H.Y. Chang, H.S. Leu (1998) An outbreak of Candida albicans fungemia in a neonatal intensive care unit. Sacnd J Infect Dis 30: 137-142.
  • A.M. Wu, J.H. Wu, S.C. Song, M.C. Tsai, A herp (1998) Studies on the binding of wheat germ agglultinin (Triticum vulgaris) to O-glycans. FEBS letters 440: 315-319.
  • J.T. Yang, C.N. Chang, T.H. Lee, J.C. Hsu, T.N. Lin, J.H. Wu* (1998) Dexamethasone inhibits ischemia-induced transient reduction of neurotrophin-3 mRNA in rat hippocampal neurons. NeuroReport 9: 3477-3480.
  • A.M. Wu, J.H. Wu, W.M. Watkins, C.P. Chen, S.C. Song, Y.Y. Chen (1998) Differential binding of human blood group Sd(a+) and Sd(a-) Tamm-Horsfall glycoproteins with Dolichos biflorus and Vicia villosa-B4 agglutinins. FEBS Letters 429: 323-326.
  • Y.C. Huang, T.Y. Lin, H.S. Leu, J.L. Wu, J.H. Wu (1998) Yeast carriage on hands of hospital personnel working in intensive care units. J. Hosp Infect 39:47-51.
  • J.H. Wu, S.C. Song, Y.Y. Chen, M.C. Tsai, E.A. Kabat, A.M. Wu (1998) Multiantennary Galb→4GlcNAc and Galb1®3GalNAc clusters as important ligands for a lectin isolated from the sponge Geodia cydonium. FEBS Letters 427: 134-138.
  • A. M. Wu, S. C. Song, S C Chang, J. H. Wu, K. S. S. Chang, E. A. Kabat (1997) Further characterization of the binding properties of a GalNAc specific lectin from Codium fragile subspecies tomentosoides. Glycobiology 7: 1061-1066.
  • A. M. Wu, J. H. Wu, S. C. Song, E. A. Kabat (1996) Bandeiraea (Griffonia) simplicifolia lectin-l, isolectin 4, reacting with Tn (GalNAcal→Ser/Thr) or galabiose (Galal-4 Gal) containing ligands. FEBS Letters. 389: 183-186.
  • J. H. Wu,  M. S.  Chern. S. K. Lo, M. S. Wen and J. T. Kao (1996) Apolipoprotein B 3'hypervariable repeat genotype: association with plasma lipid concentration, coronary artery disease, and other restriction fragment polymorphisms. Clin Chem 42:927-932.
  • J. H. Wu, W. M. Watkins, C. P. Chen and M. C. Tsai (1996) Interaction of a human blood group Sd(a-) Tamm-Horsfall glycoprotein with applied lectins. FEBS letters 384:231-234
  • A. M. Wu, J. H. Wu, W. M. Watkins, C. P. Chen and M. C. Tsai (1996) Binding properties of a blood group Le(a+) active sialoglycoprotein, purified from human ovarian cyst, with applied lectins. Biochim. Biophys. Acta 1316: 139-144.
  • A. M. Wu, S. C. Song, J. H. Wu and U. Pfuller (1995) A sheep hydatid cyst glycoprotein as receptors for three toxic lectins, as well as Abrus precatorius and Riciuns communis agglutinins. Biochim. Biophys. Acta 1243:124-128.
  • A. M. Wu, W. M. Watkins, S. C. Song, A. Herp and J. H. Wu (1995) Native and asialo-Tamm-Horsfall glycoproteins as important ligands for the detection of GalNAcb1→and Galbl→4GlcNAc active lectins. Biochem. Biophys. Res. Comm. 209:103-110.
  • A. M. Wu, F. S. Shen, A. Herp, S. C. Song and J. H. Wu (1995) Fraction A of armadillo submandibular glycoportein and its desialylated product as sialy-Tn and Tn receptors of lectins. FEBS Letters 360:211-215.
  • J. H. Wu (1995) Sequences of apolipoprotein B 3'hypervariable repeat alleles. Gene 159:235-237.
  • A. M. Wu, S. C. Song, P. Y. Hwang, J. H. Wu and U. Pfueller (1995) Interaction of Mistletoe toxic lectin-I with sialoglycoproteins. Biochem. Biophys. Res. Comm. 214:396-402.                                                                      
  • A. M. Wu, A. Herp, S. C. Song, J. H. Wu and K.S. Chang (1995) Interaction of native and asialo rat sublingual glycoproteins with lectins. Life Science 57:1841-1852.
  • A. M. Wu, S. C. Song, P. Y. Hwang, J. H. Wu, K.S.Chang (1995) Binding studies on the combining site of a GalNAc alpha l- lectin specific lectin with Thomsen-Friedenreich activity prepared from green marine algae Codium fragil subspecies tomentosoides. Eur.J.Biochem. 223: 145-151.
  • A. M. Wu, S. C. Song, J. H. Wu and E. A. Kabat (1995) Affinity of Bandeiraea (Griffonia) simplicifolia lectin-I, isolectin B4 (BSI- B4) for Galal→4Gal ligand. Biochem. Biophys. Res. Comm. 216:814- 820.
  • A. M. Wu, J. H. Wu, and F.S Shen (1994) Interaction of a novel Tn (GalNAcal→Ser/Thr) glycoprotein with Gal, GalNAc and GlcNAc specific lectins. Biochem. Biophys. Res. Comm. 198:251-256.
  • J. H. Wu, M. S. Wen, S. K. Lo and M. S. Chern (1994) Increased frequency of apolipoprotein B signal peptide sp24/24 in patients with coronary artery disease. General allele survey in the population of Taiwan and comparison with Caucasians. Clinical Genetics 45:250-254.
  • A. M. Wu, F. S Shen, A Herp and J. H. Wu (1994) Interaction of hamster submaxillary sialyl-Tn glycoproteins with Gal, GalNAc and GlcNAc specific lectins. Molecular Immunology 31:485-490.                                                              
  • M. Duk, E. Lisowska, J. H. Wu and A. M. Wu (1994) The biotin/avidin-mediated microtiter plate lectin assay with the use of chemically modified glycoprotein ligand. Analytical Biochem. 221: 266-272.
  • J. H. Wu, J. T. Kao, M. S. Wen and D. Wu (1993) Coronary artery disease risk predicted by plasma levels of high density lipoprotein cholesterol, apolipoprotein A1, apolipoprotein B and lipoprotein (a) in a general Chinese population. Clinical Chemistry 39/2:209-212.
  • J. H. Wu, A. Herp and A. M. Wu (1993) Defining carbohydrate specificity of Ricinus communis agglutinin as Galb1→4GlcNAc(II)> Galb1→3GalNAc(I)> Gala1→3Gal(B)>Galb1→3GalNAc(T). Molecular Immunology 30/4:333-339.
  • J.H. Wu, M. S. Wen, S. K. Lo and D. Wu (1993) DNA polymorphisms of apolipoprotein B in the population of Taiwan. J. Formos Med Assoc 92:330-335.
  • Deanna Moore, Kesmanee Maneewannakul, Sumit Maneewannakul, June H. Wu, Karin Ippen-Ihler and David Bradley (1990) Characterization of F-plasmid conjugative transfer gene traU. J. Bacteriology 172:4263-4270.
  • San-Hwan Chen, Xiaoxia Li, Warren S. L. Liao, June H. Wu and Lawrence Chan (1990) RNA editing of apolipoprotein B mRNA sequence specificity determined by in vitro coupled transcription editing. J. Biol. Chem 265:6811-6816.
  • June H. Wu, Clay F Semenkovich, San-Hwan Chen, Wen-Hsiung Li and Lawrence Chan (1990) Apolipoprotein B mRNA editing: Validation of a sensitive assay and developmental biology of RNA editing in the rat. J. Biol. Chem. 265:12312-12316.
  • June H. Wu and Karin Ippen-Ihler (1989) Nucleotide sequence of traQ and adjacent loci in the Escherichia coli K12 F plasmid transfer operon. J. Bacteriology 171:213-221.
  • June H. Wu, Pushpa Kathir and Karin Ippen-Ihler (1988) The product of the F plasmid transfer operon gene, traF, is a periplasmic protein. J. Bacteriology 170:3633-3639.
  • Deanna Moore, June H. Wu Pushpa Kathir, Charleen M. Hamilton and Karin Ippen-Ihler (1987) Analysis of transfer genes and gene products within the traB-traC region of the Escherichia coli fertility factor F. J. Bacteriology 169:3994-4002.
  • Sumit Maneewannakul, Pushpa kathir, Deanna Moore, Lan-Anh Le, June H. Wu and Karin Ippen-Ihler (1987) Location of F plasmid transfer operon genes traC and traW and identification of the traW product. J. Bacteriology 169:5119-5124.
  • June H. Wu, Deanna Moore, Tammy Lee and Karin Ippen-Ihler (1987) Analysis of Escherichia coli K12 F factor transfer genes: traQ, trbA and trbB. Plasmid 18:54-69.
  • Albert M. Wu, June Wu and Anthony Herp (1978) Polypeptide linkages and resulting structural features as powerful chromogenic factors in the Lowry phenol reaction. Studies on a glycoprotein containing on Lowry phenol-reactive amino acids and on its desialylated and deglycosylated products. Biochem.J. 175:47-51

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研討會論文:

  • BJ Pan, JH Wu (2010) Klebsiella pneumoniae with fucose synthesis gene mutation displays reduced virulence. The FEBS Journal 277 (Suppl 1): 91. At 35th FEBS Congress, Gothenburg, Sweden
  • JH Wu, W.X. Chen (2009) Signal transduction in HepG2 cells infected with a bacterium Klebsiella pneumoniae. The FEBS J. 276 (Suppl 1): 257. At 34th FEBS Congress, Prague, Czech Republic
  • J.H. Wu, Y.C. Fu, A.M. Wu (2009) Interaction of lipoprotein (a) and annexin A5 affects anticoagulant function of annexin A5. At 15th European Carbohydrate Symposium, Vienna, Austria
  • J.H. Wu (2008) Cell death in HepG2 cells infected with a virulent Klebsiella pneumoniae. At 48th Annual Meeting of American Society for Cell Biology, San Francisco, USA
  • Y.C Fu, J.H. Wu* (2008) Role of sugars on lipoprotein (a) in its interaction with endothelial cells.The FEBS Journal 275 (Suppl 1):244. At 33rd FEBS Congress and 11th IUBMB Conference, Athens, Greece.

 

  • Y.C Fu, J.H. Wu* (2007) The role of annexins in interaction of lipoprotein (a) with endothelial cells. At 47th Annual Meeting, American Society for Cell Biology, Washington DC, USA
  • J.H. Wu, X.Y Chang A.M. Wu (2007) In search of virulence factor of Klebsiella pneumoniae isolated from diabetic patient with liver abscess. At 107th General Meeting, American Society for Microbiology, Toronto, Canada
  • W Tang, JH Wu (2006) Interaction of intron sequences of apolipoprotein (a) repeats with HepG2 nuclear extract. At 46th Annual Meeting, the American Society for Cell Biology, San Diego, CA, USA.
  • JH Wu, CG Tsai, AM Wu, TS Wu (2006) Studies of capsular carbohydrates in Klebsiella pneumoniae isolated from a diabetic patient. The FEBS Journal 273: suppl 1 : 263. At 31st FEBS Congress Istanbul, Turkey.
  • J.H. Wu, L Hong, E. Tsai (2005) Activation of signaling molecules in Klebsiella pneumoniae-infected human hepatoma cells, HepG2. At 45th Annual Meeting America Society for Cell Biology, San Francisco,, USA
  • L.Hong, J.H. Wu (2005) Activation of MAPK signaling pathways in HepG2 cells infected with Klebsiella pneumoniae of liver abscess isolates. At 105th General Meeting, Amercian Society for Microbiology, Atlanta Georgia, USA.
  • C. Tsai, J.H. Wu (2004) Infections in diabetic mice by Klebsiella pneumoniae of liver abscess isolates. Molecular Biology of the Cell 15 Suppl: 464a
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