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Yunn-Hwa Ma (馬蘊華)


Lab:Pharmacology Laboratory


University/NationUniversity of Minnesota, Minneapolis, USA

Tel:(03)2118800 ext.5266

Research website :,c1910-1.php

Research interests:


- Magnetic nanoparticles as drug carriers for target therapeutics

- Vascular biology and signal transduction


Representative Publications:

Lu YC, Chang FY, Tu SJ, Chen JP, Ma YH*: Cellular uptake of magnetite nanoparticles enhanced by NdFeB magnets in staggered arrangement. Journal of Magnetism and Magnetic Materials 427:71-80, 2017.

Chen JP, Liu CH, Hsu HL, Wu T, Lu YJ, Ma YH*: Magnetically controlled release of recombinant tissue plasminogen activator from chitosan nanocomposites for targeted thrombolysis. Journal of Materials Chemistry B 4, 2578-2590, 2016.

Lu YC, Luo PC, Huang CW, Leu YL, Wang TH, Wei KC, Wang HE, Ma YH*: Augmented cellular uptake of nanoparticles by tea catechins: an effect of surface modification on nanoparticle-cell interaction. Nanoscale 6:10297-10306, 2014.

Tu SJ, Wu SY, Wang FS, and Ma YH*: Retention assessment of magnetic nanoparticles in rat arteries with micro computed tomography. Phys Med Biol 59: 1271-1281, 2014.

Yang HW, Hua MY, Lin KJ, Wey SP, Tsai RY, Wu SY, Lu YC, Liu HL, Wu T, Ma YH*: Bioconjugation of recombinant tissue plasminogen activator to magnetic nanocarriers for targeted thrombolysis.  International Journal of Nanomedicine 7: 5159–5173, 2012.

Chen JP, Yang PC, and Ma YH, Tu SJ and Lu YJ: Targeted delivery of tissue plasminogen activator by binding to silica-coated magnetic nanoparticle. International Journal of Nanomedicine 7:5137-5149, 2012.

Ma YH*, Chen SY, Tu SJ, Yang HW, Liu HL: Manipulation of magnetic nanoparticle retention and hemodynamic consequence in microcirculation: assessment by laser speckle imaging. International Journal of Nanomedicine 7: 2817-2827, 2012.

Liang CJ, Tseng CP, Yang CM and Ma YH*. 20-HETE inhibits ATP-induced cyclooxygenase 2 expression via peroxisome proliferator activator receptor in vascular smooth muscle cells. British Journal of Pharmacology 163:815-825, 2011.

Ma YH*, Wu SY, Wu T, Chang YJ, Hua MY, Chen JP: Magnetically targeted thrombolysis with recombinant tissue plasminogen activator bound to polyacrylic acid-coated nanoparticles. Biomaterials 30:3343-3351, 2009.

Liang CJ, Ives HE, Yang CM and Ma YH*: 20-HETE inhibits proliferation of vascular smooth muscle cells via transforming growth factor-beta. Journal of Lipid Research 49:66-73, 2008.

Ma YH, Hsu YW, Chang YJ, Hua MY, Chen JP and Wu T: Intra-arterial application of magnetic nanoparticle for targeted thrombolytic therapy: a rat embolic model. Journal of Magnetism and Magnetic Materials, 311: 342-346, 2007.

Wu T, Hua MY, Chen JP, Wei KC, Jung SM, Chang YJ, Jou MJ, Ma YH*: Effects of external magnetic field on biodistribution of nanoparticles: A histological study. Journal of Magnetism and Magnetic Materials, 311: 372-375, 2007.



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