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鄧致剛

 

http://gibms.cgu.edu.tw/ezfiles/41/1041/img/357/149880843.jpg

鄧致剛 (Petrus Tang)

職稱:教授

研究室名稱:分子調控暨生物資訊研究室 
http://gibms.cgu.edu.tw/ezfiles/41/1041/img/357/625182536.jpg

最高學歷Ph.D.

學校/國家:劍橋大學/英國

分機號碼03-2118800#5136

電子郵件帳號 petang@mail.cgu.edu.tw

個人網頁網址:http://petang.cgu.edu.tw

研究室現有: 博士後研究員0

博士班研究生3

碩士班研究生1

專任研究助理3

大學部專題生2

 

研究方向研究室特色 
分子調控暨生物資訊研究室之主要研究目標為以單細胞生物陰道鞭毛蟲作實驗材料,探討細胞壽命延長及化的調控機轉。研究特色是利用生物資訊整合各種經由高通量分析平所產生之數據對基因體、轉譯體,蛋白質體作為基礎,並從此等資料中進行探,發掘可能調命單細胞原生動物壽命延長及化的機轉。

 

最近五年所發表論文:(*第一或通信作者)

Selected Publications from 2008 :(*corresponding author , #equal contribution)

 

2013

(1)       Huang KY, Shin JW, Huang PJ, Ku FM, Lin WC, Lin R, Hsu WM, Tang P*. (2013) Functional profiling of the Tritrichomonas foetus transcriptome and proteome. Mol. Biochem. Parasitol. 187:60– 71.

(2)       Yeh YM, Huang KY, Gan RRC, Huang HD, Wang TC, Tang P*. (2013) Phosphoproteome profiling of the sexually transmitted pathogen Trichomonas vaginalis. J. Microbiol. Infect. Immunol. [doi:10.1016/j.jmii.2012.07.010]

2012

(3)       Chen CL#, Lai YF#, Tang P#, Chien KY, Yu JS, Tsai CN, Chen HW, Wu CC, Chung T, Hsu CW, Chen CD, Chang YS, Chang PL, Chen YT* (2012) Comparative and targeted proteomic analyses of urinary microparticles from bladder cancer and hernia patients. J. Proteome Res. 11(12):5611-29.

(4)       Horváthová L, Šafaříková L, Basler M, Hrdý I, Campo NB, Shin JW, Huang KY, Huang PJ, Lin R, Tang P*, Tachezy J*. (2012) Transcriptomic identification of iron-regulated and iron-independent gene copies within the heavily duplicated Trichomonas vaginalis genome. Genome Biol. Evol. 4: 905-917.

(5)       Huang KY, Huang PJ, Ku FM, Lin R. Alderete JF*, Tang P* (2012) New perspectives on the responses of Trichomonas vaginalis following adherence to fibronectin by comparative transcriptomic and proteomic analyses. Infect. Immun. 80(11):3900-3911.

(6)       Chen TW, Gan RCR, Wu TH, Huang PJ, Lee CY, Chen YYM, Chen CC and Tang P*. (2012) FastAnnotator: an efficient transcript annotation web tool. BMC Genomics Genomics 13:Suppl 8, S9

(7)       Chen TW, Gan RRC, Wu TH, Lin WC, Tang P*.(2012) VIP DB -a viral protein domain usage and distribution database. Genomics 100:149-156.

(8)       Geng J, Chiu CH, Tang P, ChenY, Shieh HR, Hu SN, and Chen YM*. (2012). Complete genome and transcriptomes of Streptococcus parasanguinis FW213: phylogenic relations and potential virulence mechanisms. PLoS ONE 7(4): e34769.

(9)       Yu D, Wang Y, Fang X, Hu S, Tang P, Fu Y* (2012) Acquisition of hydrogenosomal presequences: examples from Trichomonas vaginalis. FEMS Microbiology Letters 330(2):127-31.

(10)   Huang PJ, Lin WC, Chen SC, Lin YH, Sun CH, Lyu PC, Tang P* (2012) Identification of putative miRNA from the deep-branching unicellular flagellates. Genomics 99(2):201-207

2011

(11)   Ma L, Chen K, Meng Q, Liu Q, Tang P, Hu S, Yu J*. (2011) An evolutionary analysis of trypanosomatid GP63 proteases. Parasitol Res. 109(4):1075-84.

(12)   Chang SH, Tang P, Wang LC*. (2011) A transcriptomic study on the pepsin-activated infective larvae of Angiostrongylus cantonensis. Mol Biochem Parasitol. 179(1):47-50

(13)   Chen TH, Tang P#, Yang CF, Kao LH, Lo YP, Chuang CK, Shih YT, Chen WJ* (2011) Antioxidant defense is one of the mechanisms by which mosquito cells survive dengue 2 viral infection. Virology 410(2):410-7.

(14)   Ma L, Meng Q, Cheng W, Sung Y, Tang P, Hu S, Yu J*. (2011) Involvement of the GP63 protease in infection of Trichomonas vaginalis. Parasitol Res. 109(1): 71-79.

(15)   Chen WJ, Tang P#, Hseu YC, Chen CC,Huang KY, Chen SC* (2011) A proteome analysis of the tetracyanonickelate (II) responses in Klebsiella oxytoca. Environmental Microbiology Reports 3(1):106-111.

(16)   Tang P, Wang LC (2011) Uptake and utilization of arachidonic acid in infective larvae of Angiostrongylus cantonensis. J Helminthol. 85(4):395-400.

2010

(17)   Huang PJ, Liu YC, Lee CC, Lin WC, Gan RRC ,Lyu PL, Tang P* (2010) DSAP: Deep-Sequencing Small RNA Analysis Pipeline. Nucleic Acids Res. 38 Suppl:W385-91.

(18)   Noël CJ, Diaz N, Sicheritz-Ponten T, Safarikova L, Tachezy J, Tang P, Fiori PL, Hirt RP*. (2010) Trichomonas vaginalis BspA-like vast gene family: evidence for functional diversity. BMC Genomics 11:99.

(19)   Tang P, Hseu YC, Chou HH, Huang KY, Chen SC* (2010) Proteomic analysis of the effect of cyanide on Klebsiellaoxytoca. Curr. Microbiol. 60(3):224-228.

(20)   Tsui KH, Tang P#, Lin CY, Chang PL, Chang CH, Chiu YM, Yung, BYM* (2010) Loss of Bikunin in urine as useful marker of bladder carcinoma. J. Urology. 183, 339-344.

2009

(21)   Lin WC, Huang KY, Chen SC, Huang TY, Chen SJ, Huang PJ, Tang P*.(2009) Malate dehydrogenase is negatively regulated by miR-1 in Trichomonas vaginalis. Parasitol. Res. 105: 1683-1689.

(22)   Tse KP, Su WH, Chang KP, Tsang NM, Yu CJ, Tang P, See LC, Hsueh C, Yang ML, Hao SP, Li HY, Wang MH, Liao LP, Chen LC, Lin SR, Jorgensen TJ, Chang YS*, Shugart YY. (2009) Genome-wide Association Study Reveals Multiple Nasopharyngeal Carcinoma-Associated Loci within the HLA Region at Chromosome 6p21.3. Am J Hum Genet. 85 (2):194-203.

(23)   Feng Y, Hsiao YH, Chen HL, Chu C, Tang P, Chiu CH*. (2009) Apoptosis-like cell death induced by Salmonella in Acanthamoebarhysodes. Genomics. 94(2):132-7.

(24)   Ding F, Tang P#, Hsu MH, Cui P, Hu SN, Yu J, Chiu CH* (2009) Genome Evolution Driven by Host Adaptations Results in a More Virulent and Resistant Streptococcus pneumoniae Serotype 14. BMC Genomics 10:158. (equal contribution)

(25)   Lin WC, Li SC, Lin WC, Shin JW, Hu SN, Yu XM, Huang TY, Chen SC, Chen HC, Chen SJ, Huang PJ, Gan RRC, Chiu CH, Tang P* (2009) Identification of microRNA in the protist Trichomonas vaginalis. Genomics 93: 487–493.

(26)   Huang KY, Chien KY, Lin YC, Hsu WM, Fong IK, Huang PJ, Yueh YM, Gan RRC, Tang P*. (2009) A Proteome Reference Map of Trichomonas vaginalis. Parasitol. Res. 104(4):927-933.

(27)Lin CY, Huang MY, Chu CH, Tang P, Tang C.Y*. (2009) Mapping short reads to a genome without using hash look-up table algorithm and Burrows Wheeler Transformation. Proceedings - 2009 IEEE International Conference on Bioinformatics and Biomedicine Workshops, BIBMW 2009 , art. no. 5332100, pp. 232-237.

2008

(28)   Chen K, Meng Q, Ma L, Liu Q, Tang P, Chiu C, Hu S, Yu J*. (2008) A novel DNA sequence periodicity decodes nucleosome positioning. Nucleic Acids Res. 36:6228-6236.

(29)   Tang P, Liu JK, Chou SM,1, Hor LI, Chen WJ, Chen SC* (2008) A proteomic analysis of Klebsiellaoxytoca after exposure to succinonitrile. Process Biochemistry 43:753–757.

 

 

Book Chapters

(1)  鄧致剛*、陳玉純 (2008) 惱人的鼓脹病. 科學人. 77:

(2)  Jane M. Carlton, Shehre-Banoo Malik, Steven A. Sullivan, Thomas Sicheritz-Ponten, Petrus Tang and Robert P. Hirt (2010) The Genome of Trichomonas vaginalis in "Anaerobic Parasitic Protozoa: Genomics and Molecular Biology” edited by C. Graham Clark, Patricia J. Johnson and Rodney D. Adam. Caister Academic Press (ISBN: 978-1-904455-61-5)

 

Conferences

(A) Invited/Panel Speaker

(1)       EST Analysis of Trichomonas vaginalis ATCC30236 in "The Genome and Biology of the Trichomonads". December 3rd, 2003. Philidephia, USA.

(2)       EST Analysis of Trichomonas vaginalis in "Genomics and Biology of the Amitochondriates". September 18-19, 2004. Woods Hole, USA.

(3)       Insights from the Transcriptome of Trichomonas vaginalis in "The Third International Conference on Anaerobic Protists". September 17-20, 2005. Alghero, Italy.

(4)       Comparative Transcriptomics of Trichomonas vaginalis via EST analysis in "The XI International Congress of Parasitology". August 6-11, 2006. Glasgow, UK.

(5)       Gene Discovery and Gene Expression Profiling in Tritrichomonas foetus by Expressed Sequence Tags Analysis in “International Symposium on Parasitism and Wildlife” December 15-16, 2007, Taichung, Taiwan.

(6)       Conservation and Divergence of Flagellate microRNA in “The Fourth International Conference on Anaerobic Protists”. May 12-16, 2008. Taoyuan, Taiwan.

(7)       Integration of High-throughput Technologies for the Identification of microRNA Targets in Protist in "The 7th International Bioinformatics Workshop" June 19-21, 2009, Suzhou, China

(8)       Protist miRNA in "The Eleventh Asian-Pacific Congress for Parasitic Zoonoses" Oct 26-28, 2010, Incheon, South Korea.

(9)       Regulation of cell division cycle by glucose restriction in Trichomonas vaginalis in “The 44th U.S.-Japan Joint Conference on Parasitic Diseases, U.S.-Japan Cooperative Medical Science Program.” Jan 10-12, 2011, Tokyo Japan.

(10)   The Trichomonas vaginalis hydrogenosome proteome in “International Union of Microbiological 2011”, Sep 6-10, 2011, Sapporo, Japan.

(11)   The origin and biological role of miRNA in deep-branching unicellular flagellates in the “1st Asian Congress of Protistology (ACOP 2011)”. Oct 3-6, 2011, Jeju, Korea.

 

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