Shu-Yuan Hsu

Shu-Er Chow (周淑娥)

Appointment:Associate Professor

Lab:Biology Research Lab.


University/Nation:Taiwan Normal University/Taiwan


Research website: 

Research interests

  1. Molecular mechanism of PKCs mediated invasion and survival in human carcinoma cells
  2. ER stress response in carcinoma cells: Target studying the ER caspase and non-canonical autophagy


  1. Wang JS, Chow SE, Chen JK, Wong MK. Effect of exercise training on oxLDL-mediated platelet function in rats. Thromb Haemost 2000, 83: 503-508.
  2. Wang JS, Yang CF, Wong MK, Chow SE, and Chen JK. Effect of strenous arm exercise on oxLDL potentiated platelet activation in individuals with spinal cord injury. Thromb Haemost 2000, 84: 118-123.
  3. Chow SE, Chu WK, Shih SH and Chen JK. Exposure to oxidized LDL reduces activable Ras protein in vascular endothelial cells. In Vitro Cell Dev. Biol. 2002, 38: 320-325.
  4. Wang JS, Chow SE and Chen JK. Strenous acute exercise affects reciprocal modulation of platelet and polymorphonuclear leukocyte activities under shear flow in men. Thromb.Haemost. 2003, 1: 2031-2037.
  5. Wang JS, Chow SE. Effects of exercise training and detraining on oxidized low density lipoprotein-potentiated platelet function in men. Arch Phys Med Rehabil. 2004, 85: 1531-1537.
  6. Chen, JK and Chow SE. Antioxidants and myocardial ischemia-reperfusion injuries. CGMJ. 2005, 28: 369-377.
  7. Wang JS*, Chen YW, Chow SE, Ou HC, Sheu WH. Exercise paradoxically modulates oxidized low density lipoprotein-induced adhesion molecules expression and trans-endothelial migration of monocyte in men. Thromb Haemost. 2005, 94: 846-52.
  8. Chu WK, Lee KC, Chow SE, Chen JK. Dual regulation of theΔNp63 transcriptional activity byΔNp63 in human nasopharyngeal carcinoma cell Biochem Biophys Res Commun 2006, 342: 1356-1360.
  9. Chow SE, Hshu YC, Wang JS, Chen JK*. Resveratrol attenuates oxLDL-stimulated NADPH oxidase activity and protects endothelial cells from oxidative functional damages. J Appl Physiol. 2007, 102: 1520-7.
  10. Chen YJ, Wang JS, Chow SE*. Resveratrol protects vascular endothelial cell from ox-LDL-induced reduction in antithrombogenic activity. Chin J Physiol. 2007, 50: 22-28.
  11. Wang JS*, Chang CY, Chow SE, Chen YW, Yang CM. Exercise modulates platelet-nasopharyngeal carcinoma cell aggregation and subsequent tissue factor and matrix metalloproteinase activities. J Appl Physiol. 2007, 103: 763-70.
  12. Chiang CT, Chu WK, Chow SE, Chen JK. Overexpression of ΔNp63 in a human nasopharyngeal carcinoma cell line downregulates CKIs and enhances cell proliferation. J Cell Physiol. 2009, 219: 117-22.
  13. Wang JS, Chung Y, Chow SE. Exercise affects platelet-impeded antitumor cytotoxicity of natural killer cell. Med Sci Sports Exerc. 2009, 41: 115-122.
  14. Chow SE*, Wang,JS, Chuang SF, Chang YL, Chu WK, Chen WS and Chen YW. Resveratrol - induced p53-independent apoptosis of human nasopharyngeal carcinoma cells is correlated with down- regulation of ΔNp63. Cancer Gene Therap. 2010, 17: 872–882
  15. Chow SE*, Chang YL, Chuang SF, and Wang JS. Wogonin induced apoptosis in human nasopharyngeal carcinoma cells by targeting GSK-3β and ΔNp63. Cancer Chemother Pharm. 2010, DOI 10.1007/s00280-010-1552-1.
  16. Chow SE*, Wang JS, Lin MR, Lee CL. Downregulation of p57(kip2) promotes cell invasion via LIMK/cofilin pathway in human nasopharyngeal carcinoma cells J Cell Biochem. 2011, Jul 18. doi: 10.1002/jcb.23277.
  17. Chow SE*, Chen YW, Liang CA, Huang YK, Wang JS. Wogonin induces cross-regulation between autophagy and apoptosis via a variety of Akt pathway in human nasopharyngeal carcinoma cells. J Cell Biochem. 2012, Jun 11. doi: 10.1002/jcb.24224.
  18. Hsu. CC, Chow SE, Chen CP, Tsai WC, Wang JS, Yu SY, Lee SC. Negative Pressure Accelerated Monolayer Keratinocyte Healing Involves Cdc42 Mediated Cell Podia Formation. J Dermatol Sci 2013, March. doi: 10.1016/j.jdermsci.2013.03.007 (In presss)