郁兆蘭 (Chao-Lan Yu)

職稱

教授

最高學歷

美國密西根大學微生物及免疫博士

E-mail

clyu@mail.cgu.edu.tw

電話：

+886-3-211-8800 ext. 3730

傳真

+886-3-211-8700

實驗室

癌症研究

專長

癌症生物學、訊號傳遞與基因調控

研究方向及研究室特色

·  致癌基因與腫瘤抑制基因

·  癌細胞代謝與動物模式

·  細胞核與粒線體交互作用的分子機轉

·  葡萄糖及胰島素嵌定技術研究小鼠活體代謝

論文與著作

最近五年所發表論文：

Chueh FY, Chang YL, Wu SY, and Yu CL.  May 2020.  Signal transducer and activator of transcription 5a (STAT5a) represses mitochondrial gene expression through direct binding to mitochondrial DNA.  Biochem. Biophys. Res. Commun. 527:974-978.

Wu YH, Chuang LP, Yu CL, Wang SW, Chen HY, Chang YL.  Jun 2019.  Anticoagulant effect of wogonin against tissue factor expression.  Eur. J. Pharmacol. 859:Article 172517

Chang CW, Hsu CY, Hsu J, Ku YC, Liao TC, Lin BT, Liu TL, Lu M, Lu YH, Wang YY, Yen DL, Chang KP, Chen GW, Lee CC, Yu CL.  16 May 2017.  Leijuvant - A revolutionary choice of vaccine helper; Construction of an E. coli-Leishmania shuttle vector.  PLoS Collections: iGEM 2016.

Chang KP, Kolli BK, and the New Light Group (Batchu R, Chen HW, Chow LC, Elliott R, Head J, Fan CK, Hung CH, Ji DD, Lun ZR, Manna L, Matsumoto Y, Ng DP, de Oliveira C, Melo S, Ozbel Y, Ozbilgin A, Reynolds J, Sanjoba C, Shiao SH, Shih NY, Tsai CW, Vicente MG, Barre C, Volf P, Wu YL, Yu CL, Zhou XN).  13 July 2016.  New "light" for one-world approach toward safe and effective control of animal diseases and insect vectors from leishmaniac perspectives.  Parasite Vector 9(1):396.

Yu CL, Jove R, and Turkson J.  September 2016.  Chapter 4: Historical development of STAT3 inhibitors and early results in clinical trials.  Book title: STAT inhibitors in cancer (ISBN: 978-3-319-42947-2).  Series title: Cancer Drug Discovery and Development.  Humana Press.  Pages 69-94.