洪麗滿

      

洪麗滿 (Hung, Li-Man)

職稱：教授

研究室名稱：洪麗滿心血管研究室

最高學歷：博士

學校/國家：長庚大學/台灣

分機號碼：3338

電子郵件帳號： lisahung@mail.cgu.edu.tw

個人網頁網址：

研究室現有： 博士後研究員 1  人

博士班研究生    人

碩士班研究生 5 人

專任研究助理  2  人

大學部專題生   2  人

研究領域:

07.心血管學

41.生理

43.藥理及生理

工作經歷:

       2001-2003                     博士後研究員                          長庚醫院醫學研究員

         2003-2004                     客座助理教授                          長庚大學臨床醫學研究所

2003-2004                      博士後研究員                          長庚醫院醫學研究員

2004/5-2006/4                祕書長                                      中國生理學會

2004/2-2007/7                助理教授                 長庚大學生物醫學系

2007/8～2011/7              副教授                                      長庚大學生物醫學系

2011/8～                         教授                     長庚大學生物醫學系

學歷:

1993-1995                 碩士                長庚大學基礎醫學研究所

1996-2001                 博士        國立臺灣大學藥理所

 

最近五年所發表論文：

1.     Ma H, Zhang F, Zhou L, Cao T, Sun D, Wen S, Zhu J, Xiong Z, Tsau MT, Cheng ML, Hung LM, Zhou Y, Li Q. c-Src facilitates tumorigenesis by phosphorylating and activating G6PD. Oncogene. 2021 Mar 8.

2.     Yu-Hao Liu , Chien-Chang Chen , Yi-Jen Hsueh , Hung LM, David Hui-Kang Ma, Hung-Chi Chen, Wen-Bin Len, Yaa-Jyuhn J Meir. Extraneous E-Cadherin Engages the Deterministic Process of Somatic Reprogramming through Modulating STAT3 and Erk1/2 Activity. Cells. 31;10(2):284. 2021

3.     Chu WK, Hung LM, Hou CW, Chen JK. PKC Regulates YAP Expression through Alternative Splicing of YAP 3'UTR Pre-mRNA by hnRNP F.  Int J Mol Sci. 12;22(2):E694. 2021

4.     Huang JP, Cheng ML, Wang CH, Huang SS, Hsieh PS, Chang CC, Kuo CY, Chen KH, Hung LM* (correspondence). Therapeutic potential of cPLA2 inhibitor to counteract dilated-cardiomyopathy in cholesterol-treated H9C2 cardiomyocyte and MUNO rat. Pharmacol Res. 2020 Oct;160:105201

5.     Chang CC, Chang CY, Lin PC, Huang JP, Chen KH, Yen TH, Hung LM* (correspondence), Administration of low-dose resveratrol attenuated hepatic inflammation and lipid accumulation in high cholesterol-fructose diet-induced rat model of nonalcoholic fatty liver disease. Chin J Physiol. 63(4):149-155, 2020.

6.     Ma H, Zhang J, Zhou L, Wen S, Tang HY, Jiang B, Zhang F, Suleman M, Sun D, Chen A, Zhao W, Lin F, Tsau MT, Shih LM, Xie C, Li X, Lin D, Hung LM* (correspondence), Cheng ML, Li Q. c-Src Promotes Tumorigenesis and Tumor Progression by Activating PFKFB3. Cell Rep. 24;30(12)：4235-4249, 2020.

7.     Chan YH, Chang GJ, Lai YJ, Chen WJ, Chang SH, Hung LM, Kuo CT, Yeh YH. Atrial fibrillation and its arrhythmogenesis associated with insulin resistance. Cardiovasc Diabetol.  26;18(1):125, 2019.

8.     Huang JP, Hsu SC, Li DE, Chen KH, Kuo CY, Hung LM* (correspondence). Resveratrol Mitigates High-Fat Diet-Induced Vascular Dysfunction by Activating the Akt/eNOS/NO and Sirt1/ER Pathway. Journal of Cardiovascular Pharmacology. 72(5):231-241, 2018.

9.     Chu WK, Hung LM, Hou CW, Chen JK. Heterogeneous ribonucleoprotein F regulates YAP expression via a G-tract in 3'UTR. Biochim Biophys Acta Gene Regul Mech. S1874-9399 (18)30174-3, 2018.

10.   Chung YH, Lu KY, Chiu SC, Lo CJ, Hung LM, Huang JP, Cheng ML, Wang CH, Tsai CK, Lin YC, Chang SH, Lin G. Early Imaging Biomarker of Myocardial Glucose Adaptations in High-Fat-Diet-Induced Insulin Resistance Model by Using 18F-FDG PET and [U-13C]glucose Nuclear Magnetic Resonance Tracer. Contrast Media Mol Imaging.  Jul 12;2018

11.   Huang JP, Hsu SC, Meir YJ, Hsieh PS, Chang CC, Chen KH, Chen JK, Hung LM* (correspondence). Role of dysfunctional adipocytes in cholesterol-induced nonobese metabolic syndrome. J Mol Endocrinol. 60(4)：307-321, 2018.

12.   Yang Z, Jiang B, Wang Y, Ni H, Zhang J, Xia J, Shi M, Hung LM, Ruan J, Mak TW, Li Q, Han J. 2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter. Cell Rep. 30;19(9)：1846-1857, 2017.

13.   Jiang B, Zhang J, Xia J, Zhao W, Wu Y, Shi M, Luo L, Zhou H, Chen A, Ma H, Zhao Q, Suleman M, Lin F, Zhou L, Wang J, Zhang Y, He Y, Li X, Hung LM, Mak TW, Li Q. IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation. Cell Rep. 11;19(2)：389-400, 2017.

14.   Huang JP, Cheng ML, Hung CY, Wang CH, Hsieh PS, Shiao MS, Chen JK, Li DE, Hung LM*(correspondence). Docosapentaenoic acid and docosahexaenoic acid are positively associated with insulin sensitivity in rats fed high-fat and high-fructose diets. Journal of Diabetes.  9(10)：936-946, 2017.

15.   Jiung-Pang Huang, Mei-Ling Cheng, Chao-HungWang, Ming-Shi Shiao, Jan-Kan Chen & Hung LM*(correspondence). High-fructose and high-fat feeding correspondingly lead to the development of lysoPC-associated apoptotic cardiomyopathy and adrenergic signaling-related cardiac hypertrophy. International Journal of Cardiology. 215 (2016): 65–76, 2016.

16.   Chih-Chun Chang, Keng-Yang Lin, Kang-Yu Peng, Yuan-Ji Day & Hung LM* (correspondence). Resveratrol exerts anti-obesity in high-fat diet obese mice and displays differential dosage effects on cytotoxicity, differentiation, and lipolysis in 3T3-L1 cells. Endocrine Journal. 63 (2): 169-78, 2016.