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Lai-Chu See


Lai-Chu See

Appointment: Professor

Lab: Biostatistics

Education: Ph.D.


National Taiwan University / Taiwan

Tel: x5119

E-mail: lichu@mail.cgu.edu.tw

Research website: https://cgmmrc.cgu.edu.tw/p/406-1029-69444,r1667.php?Lang=zh-tw

Research interests

Since working at Chang Gung University in 1992 till now (September 10, 2021), I have published 388 journal articles, of which 65.2% were written in English (253 articles), and 34.8% were written in Chinese (135 articles). I was either the corresponding author or the first author in 171 articles (44.1%). My research interests are as follows:

  1. Big data

I have been working with clinicians in different disciplines using big data, including National Health Insurance Research Database (NHIRD), Taiwan Cancer Registry, Taiwan Death Registry, Taiwan Birth registry etc. My team attempted to build up real-world evidence (RWE) for different medical research topics by setting up rigorous inclusion and exclusion conditions, and adopting appropriate research designs and diverse and advanced statistical methods. It is a great honor to continue to receive funding support from the Ministry of Science and Technology and the Chang Gung Memorial Research Project. From 2011 to Sept. 2021, 79 SCI papers have been published. Among them, I was the corresponding authors (29 articles), co-corresponding authors (7 articles), or first authors (2 articles), accounting for a total of 48.1%.

  1. Public health

I have performed many public health studies by cooperating with the local government health bureaus. The projects included: newborn health, job stress of clinical staff, AIDS prevention education, hospice care, medication safety, adolescent sex, health promotion, addiction rehabilitation, suicide prevention, long-term care, attention deficit hyperactivity disorder (ADHD), etc. A total of 86 papers (10 SCI papers) have been published, of which 74 are Chinese papers (2 are TSSCI papers).

  1. Develop questionnaires

While working on some public health studies, I have developed questionnaires to collect data. So far, 14 questionnaires have been developed and established their reliability and validity, including knowledge questionnaire of the attention deficit hyperactivity disorder, knowledge and practice of self-care on liver cirrhosis, the metabolic syndrome prevention knowledge questionnaire, AIDS knowledge questionnaire, questionnaire about supporting methadone maintenance treatment, needle syringe support questionnaire, the questionnaire about the patient-based practice of patient safety, adolescent questionnaire on sexual knowledge for teenagers, questionnaire on medical workers' stress (QMWS), questionnaire of work perception about the global budget for medical employees (WPGB), organ donation questionnaire, stress index for children or adolescents with Tourette syndrome (SICATS), questionnaire about professional attitude of health care workers toward serving HIV/AIDS patients and drug users. I had published 12 Chinese papers (2 of which are TSSCI papers) and 2 SCI papers, all of which are the first and corresponding authors (9) and the first author (3) ), corresponding author (2 articles). We welcome other researchers to use our questionnaires to compare the research results with each other.

Publications for the last 5 years (only show English papers, * represent corresponding author):

1.    Siu WHS, Li PR, *See LC. Rate of condom use among sexually active adolescents: a nationwide cross-sectional study in Taiwan from 2012 to 2016. BMJ Open 2021;11(8):e047727. (SCI, Impact factor=2.692, Ranking=64/169, MEDICINE, GENERAL & INTERNAL)

2.    Chen DY, Su PJ, See LC, Liu JR, Chuang CK, Pang ST, Tseng CN, Chen SW, Hsieh IC, Chu PH, Lin YC, Hsu CL, Chang JWC, Miao Sui Lin, Pang JHS, *Hsieh MJ, *Huang WK. Gonadotropin-releasing hormone antagonist associated with lower cardiovascular risk compared with gonadotropin-releasing hormone agonist in prostate cancer: A nationwide cohort and in vitro study. The Prostate 2021;81(12):902-912. (SCI, Impact factor=4.104, Ranking=23/90, UROLOGY & NEPHROLOGY)

3.    Huang WK, Hsu HC, Chang SH, Chou WC, Chang JWC, Chen JS, Yang TS, See* LC. Real-world effectiveness of adjuvant oxaliplatin chemotherapy in stage III colon cancer: a controlled interrupted time series analysis. Frontiers in Pharmacology 2021;12. (SCI, Impact factor=5.810, Ranking=47/356, PHARMACOLOGY & PHARMACY)

4.    Lee JS, Chang ST, Shieh LC, Lim AY, Peng WS, Chen WM, Liu YH, See LC. Stereopsis and Response Times between Collegiate Table Tennis Athletes and Non-Athletes. International Journal of Environmental Research and Public Health 2021;18(12):6287. (SCI, Impact factor=3.390, Ranking=41/176, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

5.    Chen DY, Tseng CN, Hsieh MJ, Lan WC, Chuang CK, Pang ST, Chen SW, Chen TH, Chang SH, Hsieh IC, Chu PH, Wen MS, Chen JS, Chang JWC, See LC, *Huang WK. Comparison between non–vitamin K antagonist oral anticoagulants and low-molecular-weight heparin in asian individuals with cancer-associated venous thromboembolism. JAMA Network Open 2021;4(2):e2036304-e2036304. (SCI, Impact factor=8.483, Ranking=15/169, MEDICINE, GENERAL & INTERNAL)

6.    *See LC, Li HM, Chao KY, Chung CC, Li PR, Lin SR. Knowledge of attention-deficit hyperactivity disorder among the general public, parents, and primary school teachers. Medicine (Baltimore) 2021;100(12):e25245. (SCI, Impact factor=1.889, Ranking=99/169, MEDICINE, GENERAL & INTERNAL)

7.    Lee HF, Chan YH, Li PR, Liu JR, Chao TF, Wu LS, Chang SH, Yeh YH, Kuo CT, *See LC, H LGY. Oral anticoagulants and antiplatelet agents in patients with atrial fibrillation and concomitant critical limb ischemia: a nationwide cohort study. Canadian Journal of Cardiology 2021;37(1):113-121. (SCI, Impact factor=5.223, Ranking=39/142, CARDIAC & CARDIOVASCULAR SYSTEMS)

8.    Lin KK, Lee JS, Hou CH, Chen WM, Hsiao CH, Chen YW, Yeh CT, *See LC. The sociodemographic and risk factors for keratoconus: nationwide matched case-control study in taiwan, 1998-2015. American Journal of Ophthalmology 2020;223:140-148. (SCI, Impact factor=5.258, Ranking=6/62, OPHTHALMOLOGY)

9.    Tung YC, See LC, Chang SH, Liu JR, Kuo CT, *Chang CJ. Impact of bleeding during dual antiplatelet therapy in patients with coronary artery disease. Scientific Reports 2020;10(1):1-9. (SCI, Impact factor=4.379, Ranking=17/73, MULTIDISCIPLINARY SCIENCES)

10.  Shieh LC, See LC, Chang ST, Wu TC, Lee JS, Ho WH, Lim AY, Chen WM, *Liu YH. Table tennis practice reduces gender gap in eye-hand response time: a cross-sectional study. South African Journal for Research in Sport, Physical Education & Recreation 2020;42(2):109-120. (SCI, Impact factor=0.422, Ranking=99/110, SOCIAL SCIENCES, INTERDISCIPLINARY)

11.  Lin MH, Yang HY, Yen CL, Wu CY, Jenq CC, Kuo G, Peng WS, Liu JR, Tian YC, Yang CW, Anderson GF, *See LC. Pioglitazone is associated with lower major adverse cardiovascular and cerebrovascular events than DPP4-Inhibitors in diabetic patients with end-stage renal disease: a Taiwan nationwide cohort study, 2006–2016. Journal of Clinical Medicine 2020;9(11):1-13. (SCI, Impact factor=4.241, Ranking=39/169, MEDICINE, GENERAL & INTERNAL)

12.  Lee HF, Chen SW, Liu JR, Li PR, Wu LS, Chang SH, Yeh YH, Kuo CT, *Chan YH, *See LC. Major adverse cardiovascular and limb events in patients with diabetes and concomitant peripheral artery disease treated with sodium glucose cotransporter 2 inhibitor versus dipeptidyl peptidase-4 inhibitor. Cardiovascular Diabetology 2020;19(1):1-12. (SCI, Impact factor=9.951, Ranking=10/145, ENDOCRINOLOGY & METABOLISM)

13.  Chang CJ, Tung YC, Liu JR, Chang SH, Kuo CT, *See LC. Efficacy and Safety of Ticagrelor vs. Clopidogrel in East Asian Patients with Acute Myocardial Infarction: A Nationwide Cohort Study. Clinical Pharmacology & Therapeutics 2020;109(2):443-451. (SCI, Impact factor=6.875, Ranking=20/275, PHARMACOLOGY & PHARMACY)

14.  *Lin CY, See LC, Tseng CN, Wu MY, Han Y, Lu CH, Tsai FC. Surgical outcomes analysis in patients with uncomplicated acute type A aortic dissection: A 13-year institutional experience. Scientific Reports 2020;10(1):1-11. (SCI, Impact factor=4.379, Ranking=17/73, MULTIDISCIPLINARY SCIENCES)

15.  Yang T, Lei R, Li PR, Lim AY, Sun Y, Deng J, Lin SR, *See LC. Moderated mediation model from stress to burnout among health professionals. American Journal of Health Behavior 2020;44(6):765-779. (SCI, Impact factor=1.970, Ranking=111/176, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

16.  Huang WK, Liu CH, Pang ST, Liu JR, Chang JWC, Liaw CC, Hsu CL, Lin YC, *See LC. Type of androgen deprivation therapy and risk of dementia among patients with prostate cancer in Taiwan. JAMA Network Open 2020;3(8):1-15. (SCI, Impact factor=8.483, Ranking=15/169, MEDICINE, GENERAL & INTERNAL)

17.  Yen CL, Wu CY, See LC, Li YJ, Tseng MH, Peng WS, Liu JR, Chen YC, Yen TH, Tian YC, Yang CW, Anderson GF, *Yang HY. Pioglitazone reduces mortality and adverse events in patients with type 2 diabetes and with advanced chronic kidney disease: national cohort study  (letter). Diabetes Care 2020;43(10):e152-e153. (SCI, Impact factor=19.112, Ranking=5/145, ENDOCRINOLOGY & METABOLISM)

18.  Padua PF, Lin CC, Chien HT, Young CK, Kuo CF, See LC, Luo SF, Huang LH, *Huang SF. Familial Aggregation of Head and Neck Cancer in Taiwan. Laryngoscope 2020;131(4):806-812. (SCI, Impact factor=3.325, Ranking=9/44, OTORHINOLARYNGOLOGY)

19.  Chan YH, Wu LS, See LC, Liu JR, Chang SH, Chao TF, Yeh YH, Kuo CT, *Lee HF, *Lip GYH. Direct oral anticoagulants in atrial fibrillation patients with concomitant hyperthyroidism. Journal of Clinical Endocrinology & Metabolism 2020;105(9). (SCI, Impact factor=5.958, Ranking=28/145, ENDOCRINOLOGY & METABOLISM)

20.  Lee JS, Chen WM, Huang LH, Chung CC, Yu Ku, Kuo Cu, *See LC. Epidemiology of outpatient and inpatient eye injury in Taiwan: 2000, 2005, 2010, and 2015. PLOS ONE 2020;15(7):e0235208. (SCI, Impact factor=3.240, Ranking=26/73, MULTIDISCIPLINARY SCIENCES)

21.  Tung YC, See LC, Chang SH, Tu HT, Chan YH, *Chang CJ. All-cause mortality and the risk of stroke with selective aspiration thrombectomy in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: a nationwide retrospective cohort study. Medicine (Baltimore) 2020;99(22):e19590. (SCI, Impact factor=1.889, Ranking=99/169, MEDICINE, GENERAL & INTERNAL)

22.  Lee JS, *See LC. An invited commentary on" The relationship between anesthesia technique and perioperative mortality in patients undergoing non-cardiac and non-neuro surgery: A retrospective, propensity score-matched cohort study”. International Journal of Surgery 2020;78:162-163. (SCI, Impact factor=6.071, Ranking=15/212, SURGERY)

23.  Chan YH, Lee HF, Li PR, Liu JR, Chao TF, Wu LS, Chang SH, Yeh YH, Kuo CT, *See LC, *Lip GYH. Effectiveness, safety, and major adverse limb events in atrial fibrillation patients with concomitant diabetes mellitus treated with non-vitamin K antagonist oral anticoagulants. Cardiovascular Diabetology 2020;19(1):63. (SCI, Impact factor=9.951, Ranking=10/145, ENDOCRINOLOGY & METABOLISM)

24.  Huang WK, Chang SH, Hsu HC, Chou WC, Yang TS, Chen JS, Chang JWC, Lin YC, Kuo CF, *See LC. Postdiagnostic metformin use and survival of patients with colorectal cancer: a nationwide cohort study. International Journal of Cancer 2020;147(7):1904-1916. (SCI, Impact factor=7.396, Ranking=42/242, Oncology)

25.  See LC, Lee HF, Chao TF, Li PR, Liu JR, Wu LS, Chang SH, Yeh YH, Kuo CT, *Chan YH, *Lip GYH. Effectiveness and safety of direct oral anticoagulants in an Asian population with atrial fibrillation undergoing dialysis: a population-based cohort study and meta-analysis. Cardiovascular Drugs and Therapy 2020. (SCI, Impact factor=3.727, Ranking=61/141, CARDIAC & CARDIOVASCULAR SYSTEMS)

26.  *Lin CY, Lu CH, Lee HA, See LC, Wu MY, Han Y, Tseng CN, Su IL, Li HY, Tsai FC. Elderly versus non-elderly patients undergoing surgery for left-sided native valve infective endocarditis: A 10-year institutional experience. Scientific Reports 2020;10(1):1-9. (SCI, Impact factor=4.379, Ranking=17/73, MULTIDISCIPLINARY SCIENCES)

27.  *Lin YK, Chang SH, Yang CY, See LC, Lee BH, Shih IH. Efficacy and safety of indigo naturalis ointment in Treating Atopic Dermatitis: A randomized clinical trial. Journal of Ethnopharmacology 2020;250:112477. (SCI, Impact factor=4.360, Ranking=19/63, CHEMISTRY, MEDICINAL)

28.  Liu YH, *See LC, Chen SC, Chang ST, Lee JS, Shieh LC, Lim AY, Chen WM. Effectiveness of visuomotor program via light signal on simple and choice static eye-hand response time among collegiate karate kumite athletes: pretest-posttest design with a control group. Archives of Budo 2019;15:293-301. (SCI, Impact factor=1.113, Ranking=80/88, Sports Sciences)

29.  Chang YT, Wang HS, Liu JR, Tseng CN, Chou IJ, Luo SF, Kuo CF, *See LC. Association of maternal ethnicity and urbanicity on severe pediatric disease: A nationwide cohort study. BMC Pediatrics 2019;19(1):514-523. (SCI, Impact factor=2.125, Ranking=70/129, PEDIATRICS)

30.  *Tsai LH, See LC, Chien CC, Chen CM, Chang SH. Risk factors for restless legs syndrome in hemodialysis patients in Taiwan: A case-control study. Medicine (Baltimore) 2019;98(51). (SCI, Impact factor=1.889, Ranking=99/169, MEDICINE, GENERAL & INTERNAL)

31.  Lee HF, See LC, Li PR, Liu JR, Chao TF, Chang SH, Wu LS, Yeh YH, Kuo CT, *Chan YH, *Lip GYH. Non-Vitamin K Antagonist Oral Anticoagulants and Warfarin in Atrial Fibrillation Patients with Concomitant Peripheral Artery Disease. European Heart Journal - Cardiovascular Pharmacotherpy 2021;7(1):50-58. (SCI, Impact factor=6.617, Ranking=23/275, PHARMACOLOGY & PHARMACY)

32.  Chan YH, Lee HF, Chao TF, Wu CT, Chang SH, Yeh YH, See LC, Kuo CT, Chu PH, *Wang CL, *Lip GYH. Real-world comparisons of direct oral anticoagulants for stroke prevention in asian patients with non-valvular atrial fibrillation: a systematic review and meta-analysis. Cardiovascular Drugs and Therapy 2019;33(6):701-710. (SCI, Impact factor=3.727, Ranking=61/141, CARDIAC & CARDIOVASCULAR SYSTEMS)

33.  Chang SH, Wu CCV, Yeh YH, Kuo CF, Chen YL, Wen MS, See LC, *Huang YT. Efficacy and safety of oral anticoagulants in patients with atrial fibrillation and stages 4 or 5 chronic kidney disease. American Journal of Medicine 2019;132(11):1335-1343. (SCI, Impact factor=4.965, Ranking=30/169, MEDICINE, GENERAL & INTERNAL)

34.  Chan YH, Lee HF, See LC, Tu HT, Chao TF, Yeh YH, Wu LS, *Kuo CT, Chang SH, Lip GYH. Effectiveness and safety of four direct oral anticoagulants in Asian patients with nonvalvular atrial fibrillation. Chest 2019;156(3):529-543. (SCI, Impact factor=9.410, Ranking=6/64. RESPIRATORY SYSTEM)

35.  Chou IJ, Kong SS, Chung TT, See LC, Kuo CF, Lin JJ, Wang HS, Lin KL, *Hung PC, Group PS. Evaluation of the effect of the child protection act on serious child physical abuse in Taiwan. Child Abuse & Neglect 2019;95:1-11. (SCI, Impact factor=3.928, Ranking=2/44, SOCIAL WORK)

36.  Hsiao CC, Tu HT, Lin CH, Chen KH, Yeh YH, *See LC. Temporal trends of severe hypoglycemia and subsequent mortality in patients with advanced diabetic kidney diseases transitioning to dialysis. Journal of Clinical Medicine 2019;8(4):1-12. (SCI, Impact factor=4.241, Ranking=39/169, MEDICINE, GENERAL & INTERNAL)

37.  Lee HF, Chan YH, Chang SH, Tu HT, Chen SW, Yeh YH, Wu LS, Kuo CF, Kuo CT, *See LC. Effectiveness and safety of non-vitamin K antagonist oral anticoagulant and warfarin in cirrhotic patients with nonvalvular atrial fibrillation. Journal of the American Heart Association 2019;8(5):1-11. (SCI, Impact factor=5.501, Ranking=35/141, CARDIAC & CARDIOVASCULAR SYSTEMS)

38.  Wang CL, Wu VCC, Lee CH, Kuo CF, Chen YL, Chu PH, Chen SW, Wen MS, See LC, *Chang SH. Effectiveness and safety of non-vitamin-K antagonist oral anticoagulants versus warfarin in atrial fibrillation patients with thrombocytopenia. Journal of Thrombosis and Thrombolysis 2018;47(4):512-519. (SCI, Impact factor=2.300, Ranking=92/141, CARDIAC & CARDIOVASCULAR SYSTEMS)

39.  *Liu YH, See LC, Chang ST, Lee JS, Shieh LC, Ning YL, Lim AY, Chen WM. Simple and choice response time among elite and novice karate athletes and non-athletes. Archives of Budo 2018;14:267-276. (SCI, Impact factor=1.113, Ranking=76/85, Sports Sciences)

40.  Hou CH, Lee JS, Lin KK, Chang SH, Huang WK, Kuo CF, *See LC. Endophthalmitis incidence of cancer patients after cataract surgery: A nationwide matched cohort study in Taiwan. American Journal of Ophthalmology 2018;199:246-254. (SCI, Impact factor=5.258, Ranking=6/62, OPHTHALMOLOGY)

41.  Lee KT, *Chang SH, Yeh YH, Tu HT, Chan YH, Kuo CT, *See LC. The CHA2DS2-VASc score predicts major bleeding in non-valvular atrial fibrillation patients who take oral anticoagulants. Journal of Clinical Medicine 2018;7(10):1-9. (SCI, Impact factor=4.241, Ranking=39/169, MEDICINE, GENERAL & INTERNAL)

42.  Kuo CF, Chou IJ, Grainge MJ, Luo SF, See LC, Yu KH, Zhang W, Doherty M, *Valdes AM. Familial aggregation and heritability of type 1 diabetes mellitus and coaggregation of chronic diseases in affected families. Clinical Epidemiology 2018;10:1447-1455. (SCI, Impact factor=4.790, Ranking=37/203, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

43.  Chan YH, Yeh YH, Hsieh MY, Chang CY, Tu HT, Chang SH, See LC, *Kuo CF, *Kuo CT. The risk of acute kidney injury in Asians treated with apixaban, rivaroxaban, dabigatran, or warfarin for non-valvular atrial fibrillation: A nationwide cohort study in Taiwan. International Journal of Cardiology 2018;265:83-89. (SCI, Impact factor=4.164, Ranking=57/194, CARDIAC & CARDIOVASCULAR SYSTEMS)

44.  Liu FC, Lin HT, Kuo CF, Hsieh MY, See LC, *Yu HP. Familial aggregation of Parkinson's disease and coaggregation with neuropsychiatric diseases: a population-based cohort study. Clinical Epidemiology 2018;30(10):631-641. (SCI, Impact factor=4.790, Ranking=37/203, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

45.  Wu VCC, *Chang SH, Kuo CF, Liu JR, Chen SW, Yeh YH, Luo SF, *See LC. Suicide death rates in patients with cardiovascular diseases – A 15-year nationwide cohort study in Taiwan. Journal of Affective Disorders 2018;238:187-193. (SCI, Impact factor=4.839, Ranking=36/251, PSYCHIATRY)

46.  Lee HF, See LC, Chan YH, Yeh YH, Wu LS, Liu JR, Tu HT, Wang CL, Kuo CT, *Chang SH. End-stage renal disease patients using angiotensin-converting enzyme inhibitors and angiotensin receptor blockers may reduce the risk of mortality: A Taiwanese Nationwide cohort study. Internal Medicine Journal 2018;48(9):1123-1132. (SCI, Impact factor=2.048, Ranking=95/169, MEDICINE, GENERAL & INTERNAL)

47.  Lee YS, See LC, Chang SH, Wang NK, Hwang YS, Lai CC, Chen KJ, *Wu WC. Macular structures, optical components, and visual acuity in preschool children after intravitreal bevacizumab or laser treatment. American Journal of Ophthalmology 2018;192:20-30. (SCI, Impact factor=5.258, Ranking=6/62, OPHTHALMOLOGY)

48.  Huang WK, Juang YY, Chung CC, Chang SH, Chang JWC, Lin YC, Wang HM, Chang HK, Chen JS, Tsai CS, Yu KH, Kuo CF, *See LC. Timing and risk of mood disorders requiring psychotropics in long-term survivors of adult cancers: A nationwide cohort study. Journal of Affective Disorders 2018;236:80-87. (SCI, Impact factor=4.839, Ranking=36/251, PSYCHIATRY)

49.  Lee HF, Chan YH, Tu HT, Kuo CT, Yeh YH, Chang SH, Wu LS, *See LC. The effectiveness and safety of low-dose rivaroxaban in Asians with non-valvular atrial fibrillation. International Journal of Cardiology 2018;261:78-83. (SCI, Impact factor=4.164, Ranking=57/194, CARDIAC & CARDIOVASCULAR SYSTEMS)

50.  Chan YH, See LC, Tu HT, Yeh YH, Chang SH, Wu LS, Lee HF, Wang CL, Kuo CF, *Kuo CT. Efficacy and safety of apixaban, dabigatran, rivaroxaban, and warfarin in Asians with non-valvular atrial fibrillation. Journal of the American Heart Association 2018;7(8):1-16. (SCI, Impact factor=5.501, Ranking=35/141, CARDIAC & CARDIOVASCULAR SYSTEMS)

51.  Chang CY, Yeh YH, Chan YH, Liu JR, Chang SH, Lee HF, Wu LS, Yen KC, Kuo CT, *See LC. Dipeptidyl peptidase-4 inhibitor decreases the risk of atrial fibrillation in patients with type 2 diabetes: A nationwide cohort study in Taiwan. Cardiovascular Diabetology 2017;16(1):159. (SCI, Impact factor=9.951, Ranking=10/145, ENDOCRINOLOGY & METABOLISM)

52.  Wu AL, See LC, Hsia SH, Tu HT, Wang NK, Huang JL, Hwang YS, Lai CC, *Wu WC. Pediatric Abusive Head Trauma in Taiwan: Clinical Characteristics and Risk Factors Associated with Mortality. Graefe's Archive for Clinical and Experimental Ophthalmology 2018;256(5):997-1003. (SCI, Impact factor=2.396, Ranking=23/60, OPHTHALMOLOGY)

53.  Lee NC, Chang YH, Tu HT, Kuo CF, Yu KH, *See LC. Comparison of the implementation of extra root canal treatment before and after fee schedule change in the Taiwan National Health Insurance System. Journal of Dental Sciences 2017;13(2):145-150. (SCI, Impact factor=1.034, Ranking=83/91, Dentistry, oral surgery & medicine)

54.  Chan YH, Yeh YH, Tu HT, Kuo CT, Chang SH, Wu LS, Lee HF, *See LC. Bleeding risk with dabigatran, rivaroxaban, warfarin, and antiplatelet agent in Asians with non-valvular atrial fibrillation. Oncotarget 2017;8(58):98898–98917. (NO SCI, Impact factor=5.168)

55.  Chang SH, Chou IC, Yeh YH, Chiou MJ, Wen MS, Kao CH, See LC, *Kuo CF. Association between use of non–vitamin k oral anticoagulants with and without concurrent medications and risk of major bleeding in nonvalvular atrial fibrillation. JAMA 2017;318(13):1250-1259. (SCI, Impact factor=45.540, Ranking=3/155, Medicine, general & internal)

56.  *Lin YK, See LC, Huang YH, Chi CC, Hui RC. Comparison of indirubin concentrations in indigo naturalis ointment for psoriasis treatment: a randomized, double-blind, dosage-controlled trial. British Journal of Dermatology 2017;178(1):124-131. (SCI, Impact factor=7.000, Ranking=4/68, DERMATOLOGY)

57.  Kao WH, Hong JH, See LC, Yu HP, Hsu JT, Chou IJ, Chou WC, Chiou MJ, *Kuo CF. Validity of cancer diagnosis in the National Health Insurance database compared with the linked National Cancer Registry in Taiwan. Pharmacoepidemiology and Drug Safety 2017;27(10):1060-1066. (SCI, Impact factor=2.918, Ranking=54/193, PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH)

58.  *Lee KT, *Yeh YH, Chang SH, See LC, Lee CH, Wu LS, Liu JR, Kuo CT, Wen MS. Metformin is associated with fewer major adverse cardiac events among patients with a new diagnosis of type 2 diabetes mellitus: A propensity score-matched nationwide study. Medicine (Baltimore) 2017;96(28):e7507. (SCI, Impact factor=1.889, Ranking=99/169, MEDICINE, GENERAL & INTERNAL)

59.  Chen DY, See LC, Liu JR, Chuang CK, Pang ST, Hsieh IC, Wen MS, Chen TH, Lin YC, Liaw CC, Hsu CL, Chang JWC, Kuo CF, *Huang WK. Risk of cardiovascular ischemic events after surgical castration and gonadotropin-releasing hormone agonist therapy for prostate cancer: A nationwide cohort study. Journal of Clinical Oncology 2017;35(32):3697-3705. (SCI, Impact factor=32.956, Ranking=5/244, ONCOLOGY)

60.  Chang SH, Kuo CF, Chou IJ, See LC, Yu KH, Luo SF, Huang LH, Zhang W, Doherty M, Wen MS, Kuo CT, *Yeh YH. Association of a family history of atrial fibrillation with incidence. JAMA Cardiology 2017;2(8):863-870. (SCI, Impact factor=12.794, Ranking=6/138, CARDIAC & CARDIOVASCULAR SYSTEMS)

61.  Tsai HI, Liu FC, Lee CW, Kuo CF, See LC, Chung TT, *Yu HP. Cardiovascular disease risk in patients receiving organ transplantation: A national cohort study. Transplant International 2017;30(11):1161-1171. (SCI, Impact factor=3.177, Ranking=42/210, SURGERY)

62.  Chen TW, Lee CC, Liu H, Wu CS, Curtis P, Huang PJ, Chang JW, Ian , Yeh Y, Chen CD, Li HP, Luo JD, Tan B, Chan TEH, Hsueh C, Lichieh C, Chen YT, Zhang B, Yang CY, Wu CC, Hsu CW, See LC, Tang P, Yu JS, Liao WC, Chiang K, Rodriguez H, Myers J, *Chang KP, *Chang YS. APOBEC3A is an oral cancer prognostic biomarker in carriers of an APOBEC deletion polymorphism. Nature Communications 2017;8(1):1-13. (SCI, Impact factor=12.121, Ranking=6/71, MULTIDISCIPLINARY SCIENCES)

63.  Kuo CF, Lin YS, Chang SH, Chou IJ, Luo SF, See LC, Yu KH, Huang LS, *Chu PH. Familial aggregation and heritability of congenital heart defects. Circulation Journal 2017;82(1):232-238. (SCI, Impact factor=2.540, Ranking=64/138, CARDIAC & CARDIOVASCULAR SYSTEMS)

64.  Lee YS, Chang S, Wu SC, See LC, Chang SH, Yang ML, *Wu WC. The inner retinal structures of the eyes of children with a history of retinopathy of prematurity. Eye 2017;32(1):104-112. (SCI, Impact factor=2.455, Ranking=22/60, OPHTHALMOLOGY)

65.  Liu YH, Chang ST, Chen SC, Lim AY, Chang CW, *See LC. Training effect of a stationary preprogrammed target dummy on visual response time and contest performance of karate athletes. Journal of Sports Medicine and Physical Fitness 2017;57(11):1445-1455. (SCI, Impact factor=1.432, Ranking=67/85, SPORT SCIENCES)

66.  Chang SHL, Lee YS, Wu SC, See LC, Chung CC, Yang ML, Lai CC, *Wu WC. Anterior chamber angle and anterior segment structure of eyes in children with early stages of retinopathy of prematurity. American Journal of Ophthalmology 2017;179:46-54. (SCI, Impact factor=5.258, Ranking=6/62, OPHTHALMOLOGY)

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