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Hsuan Liu

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<p align="center" style="text-align:center"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:22.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Hsuan&nbsp;Liu</span></span></span></b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Appointment :</span></span></span></b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">&nbsp;Professor</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p><span style="font-size:12pt"><span style="background:whitesmoke"><span style="vertical-align:top"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Lab</span></span></b><span style="font-family:標楷體"><span style="color:#444444">:</span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">functional and cancer genomic lab</span></span></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Education :&nbsp;</span></span></span></b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Ph.D.</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">University/Nation</span></span></span></b><b><span style="font-size:11.0pt"><span style="font-family:標楷體"><span style="color:#444444">:</span></span></span></b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Institute of Molecular Medicine, National Taiwan University, Taiwan</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Tel:</span></span></span></b><b><span lang="EN-US" style="font-size:11.0pt"><span style="background:#fcfcf8"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#333333">+886-3-211-8800</span></span></span></span></b><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#2c2b2b">&nbsp;ext.</span></span></span></b><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">3526</span></span></span></b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="PT-BR" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">E-mail :</span></span></span></b>&nbsp;<span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"><a href="mailto:liu-hsuan@mail.cgu.edu.tw"><span style="font-size:11.0pt"><span style="color:#954f72">liu-hsuan@mail.cgu.edu.tw</span></span></a></span></span></span></span></p>
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<p style="margin-bottom:10px"><span style="font-size:12pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Research website :&nbsp;</span></span></span><a href="https://cgmmrc.cgu.edu.tw/p/406-1029-69430,r1661.php?Lang=zh-tw" title="劉"><span lang="EN-US" style="font-size:12.0pt"><span style="font-family:標楷體">https://cgmmrc.cgu.edu.tw/p/406-1029-69430,r1661.php?Lang=zh-tw</span></span><span lang="EN-US" style="font-size:11.0pt"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></a></b></span></span></p>
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<p><span style="font-size:1em;"><span style="line-height:12.0pt"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Research interests:</span></span></span></b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></span></p>

<p><span style="font-size:1em;"><span style="line-height:12.0pt"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">At the molecular level, the hallmark of tumor malignancy comprises dysregulation of several cellular signaling networks attributable to genetic and epigenetic changes. Recent next-generation or deep sequencing (NGS) studies have provided a more global view of the genetic and epigenetic origins of different cancer. My research is focused mainly on establishing and applying various NGS-based technologies to systematically profile nucleotide variants (at the genome or transcriptome level) in cancer samples, and explore the disease relevance of these mutational &ldquo;bio-signatures&rdquo;. Major research aims and platforms include, but not limited to:</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">1.&nbsp;&nbsp;&nbsp;&nbsp;Targeted genome re-sequencing analysis of oral squamous cell carcinoma</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">2.&nbsp;&nbsp;&nbsp;&nbsp;Targeted genome re-sequencing analysis of colorectal cancer</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">3.&nbsp;&nbsp;&nbsp;&nbsp;Targeted genome re-sequencing analysis of nasopharyngeal cancer</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">4.&nbsp;&nbsp;&nbsp;&nbsp;Transcriptomic sequencing (RNA-seq) analysis of host response to EV71 infection</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">5.&nbsp;&nbsp;&nbsp;&nbsp;RNA-seq and small RNA-seq of tissues derived from oral cancer animal model</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px; margin-left:31px; text-indent:-23.1pt"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">6.&nbsp;&nbsp;&nbsp;&nbsp;Small RNA-seq analysis of urine samples from acute kidney injury and chronic kidney disease</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">7.&nbsp;&nbsp;&nbsp;&nbsp;RNA-IP-seq analysis of RNA-binding protein-associated RNAs</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>

<p style="margin-bottom:10px"><span style="font-size:1em;"><span style="font-family:Calibri,sans-serif"><span lang="EN-US"><span style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">We complement these functional genomic experiments with cell-based and animal studies to further delineate molecular mechanisms underlying the pathological roles of these variants. Our ultimate goal is to uncover sequence variants and/or gene regulatory mechanisms that are novel diagnostic or therapeutic targets. Furthermore, we aim to establish close integration of proteomic and genomic data generated by the Molecular Medicine Research Center for translational medicine application.</span></span></span><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></p>
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<p style="margin-right:34px; margin-left:45px; text-align:justify; text-indent:-33.85pt"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="font-family:Calibri,sans-serif"><b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444">Publications:</span></span></b><span lang="EN-US" style="font-family:&quot;Times New Roman&quot;,&quot;serif&quot;"><span style="color:#444444"></span></span></span></span></span></p>

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<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chiang S-F, Huang HH, Tsai W-S, Chin-Ming Tan B, Yang C-Y, Huang P-J, Yi-Feng Chang I, Lin J, Lu P-S, Chin E, Liu Y-H, Yu J-S, Chiang J-M, Hung H-Y, <b><u>Liu H*</u></b> (2021, Mar). Comprehensive functional genomic analyses link APC somatic mutation and mRNA-miRNA networks to the clinical outcome of stage-III colorectal cancer patients. <i>Biomedical Journal</i>, Available online 16 March 2021. MOST 106-2320-B-182-035-MY3. <span style="font-family:標楷體">本人為通訊作者</span>. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Min-Hua Tseng, Wen-Lang Fan, <b><u>Hsuan Liu</u></b>, Chia-Yu Yang, Jhao-Jhuang Ding , Hwei-Jen Lee , Shih-Ming Huang, Shih-Hua Lin and Jing-Long Huang (2021, Feb). Complement Factor I Mutation May Contribute to Development of Thrombotic Microangiopathy in Lupus Nephritis. <i>Frontiers in Medicine</i>, Feb 5;7:621609. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Wen-Sy Tsai, Wei-Shan Hung, Tzu-Min Wang, <b><u>Hsuan Liu</u></b>, Chia-Yu Yang, Shao-Min Wu, Hsueh-Ling Hsu, Yu-Chiao Hsiao, Hui-Ju Tsai, Ching-Ping Tseng (2020, Oct). Circulating tumor cell enumeration for improved screening and disease detection of patients with colorectal cancer. <i>Biomedical Journal</i>. MOST 106-2320-B-182-027-MY3. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chen YT, Chang IY, Kan CH, Liu YH, Kuo YP, Tseng HH, Chen HC, <b><u>Liu H</u></b>, Chang YS, Yu JS, Chang KP, Tan BC. (2020, Aug). circRNAome Profiling in Oral Carcinoma Unveils a Novel circFLNB that Mediates Tumour Growth-Regulating Transcriptional Response. <i>Cells</i>, 10;9(8):1868. MOST 106-2320-B-182-035-MY3. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Yang CY, Liu CR, Chang IY, OuYang CN, Hsieh CH, Huang YL, Wang CI, Jan FW, Wang WL, Tsai TL, <b><u>Liu H</u></b>, Tseng CP, Chang YS, Wu CC, Chang KP (2020, Jun). Cotargeting CHK1 and PI3K Synergistically Suppresses Tumor Growth of Oral Cavity Squamous Cell Carcinoma in Patient-Derived Xenografts. <i>Cancers (Basel)</i>, 29;12(7):1726.. MOST 107-2314-B-182-075-MY3. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Wu SM, Tsai WS, Chiang SF, Lai YH, Ma CP, Wang JH, Lin J, Lu PS5, Yang CY, Tan BC, <b><u>Liu H*</u></b> (2020, Mar). Comprehensive transcriptome profiling of Taiwanese colorectal cancer implicates an ethnic basis for pathogenesis. <i>Sci Rep</i>, 10(1):4526. MOST 106-2320-B-182-035-MY3.<span style="font-family:標楷體">本人為通訊作者</span>. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chung AK, OuYang CN, <b><u>Liu H</u></b>, Chao M, Luo JD, Lee CY, Lu YJ, Chung IC, Chen LC, Wu SM, Tsang NM, Chang KP, Hsu CL, Li HP, Chang YS. (2019, Sep). Targeted sequencing of cancer-related genes in nasopharyngeal carcinoma identifies mutations in the TGF-&beta; pathway. <i>Cancer Medicine</i>, 8(11):5116-5127. MOST 105-2320-B-182-034-MY3. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Kuo YP, Ma CP, Chen HW, Chen YT, Lai YH, <b><u>Liu H</u></b>, Kuo RL, Chin-Ming Tan B. (2019, Sep). A novel antisense RNA ASPACT confers multi-level suppression of PACT and associated signalling. <i>RNA Biology</i>, 16(9):1263-1274. (SCI). </span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Ma CP, <b><u>Liu H</u></b>, Yi-Feng Chang, Wang WC, Chen YT, Wu SM, Chen HW, Kuo YP, Shih CT, Li CY, Tan BC. (2019, May). ADAR1 promotes robust hypoxia signaling via distinct regulation of multiple HIF-1&alpha;-inhibiting factors.<i>EMBO Report</i>, 20(5): pii: e47107. MOST 106-2320-B-182-042-MY3. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Lai CY*, <b><u>Liu H</u></b>*, Tin KX, Huang Y, Yeh KH, Peng HW, Chen HD, He JY, Chiang YJ, Liu CS, Weng SY, Tao MH, Yen JJ, Yang-Yen HF. (2019, Jan). Identification of UAP1L1 as a critical factor for protein O-GlcNAcylation and cell proliferation in human hepatoma cells. . <i>Oncogene</i>, 38(3):317-331.. MOST 102-2320-B-001-024-MY3. <span style="font-family:標楷體">本人為第一作者</span>. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> You GR, Cheng AJ, Lee LY, Huang YC, <b><u>Liu H</u></b>, Chen YJ, Chang JT. (2019, Jan). Prognostic signature associated with radioresistance in head and neck cancer via transcriptomic and bioinformatic analyses. <i>BMC Cancer</i>, 19(1):64. (SCI). </span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Huang YW, Chiang MF, Ho CS, Hung PL, Hsu MH, Lee TH, Chu JL, <b><u>Liu H</u></b>, Tang P, Ng VW, Lin DS (2018, Dec). A Transcriptome Study of Progeroid Neurocutaneous Syndrome Reveals POSTN As a New Element in Proline Metabolic Disorder. <i>Aging and Disease</i>, 9(6):1043-1057. (SCI). </span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chao A, Lin CY, Wu RC, Lee YS, Lee LY, Tsai CL, Yang LY, <b><u>Liu H</u></b>, Chen SJ, Wang TH, Lai CH (2018, Nov). The combination of everolimus and terameprocol exerts synergistic antiproliferative effects in endometrial cancer: molecular role of insulin-like growth factor binding protein 2. <i>J Mol Med (Berl)</i>, 96(11):1251-1266. MOST 105-2320-B-182A-005. (SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chang S, Bok P, Tsai CY, Sun CP, <b><u>Liu H</u></b>, Deussing JM, Huang GJ (2018, Aug). NPTX2 is a key component in the regulation of anxiety. <i>Neuropsychopharmacology</i>, 43(9):1943-1953. (SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chen YT, Chang IY, <b><u>Liu H</u></b>, Ma CP, Kuo YP, Shih CT, Shih YH, Kang L, Tan BC (2018, Jun). Tumor-associated intronic editing of HNRPLL generates a novel splicing variant linked to cell proliferation. <i>J Biol Chem</i>, 293(26) 10158&ndash;10171. MOST 105-2320-B-182-017. (SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Yang CY, Yeh YM, Yu HY, Chin CY, Hsu CW, <b><u>Liu H</u></b>, Huang PJ, Hu SN, Liao CT, Chang KP, Chang YL. (2018, May). Oral Microbiota Community Dynamics Associated With Oral Squamous Cell Carcinoma Staging. <i>Front Microbiol</i>, 9:862. (SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Tsai KW, Lo YH, <b><u>Liu H</u></b>, Yeh CY, Chen YZ, Hsu CW, Chen WS, Wang JH (2018, Mar). Linc00659, a long noncoding RNA, acts as novel oncogene in regulating cancer cell growth in colorectal cancer. <i>Molecular Cancer</i>, 17(1):72. (SCI). </span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Lai YH, <b><u>Liu H</u></b>, Chiang WF, Chen TW, Chu LJ, Yu JS, Chen SJ, Chen HC, Tan BC (2018, Jan). MiR-31-5p-ACOX1 Axis Enhances Tumorigenic Fitness in Oral Squamous Cell Carcinoma Via the Promigratory Prostaglandin E2. <i>Theranostics</i>, 8(2):486-504. MOST 106-2320-B-182-035-MY3. (SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Wu SM*,<b><u> Liu H*</u></b>, Huang PJ, Chang IY, Lee CC, Yang CY, Tsai WS, Tan BC. (2018, Jan). circlncRNAnet: An integrated web-based resource for mapping functional networks of long or circular forms of non-coding RNAs. , 7 (1):1-10. MOST 106-2320-B-182-035-MY3. <span style="font-family:標楷體">本人為第一作者</span>(SCI).</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chen TW*, Lee CC*, <b><u>Liu H</u></b>*, Wu CS*, Pickering CR*, Huang PJ, Wang J, Chang YF, Yeh YM, ChenCD, Li HP, Luo JD, Tan BC, Chan EH, Hsueh C, Chu LJ, Chen YT, Zhang B, Yang CY, Wu CC, Hsu CW, See LC, Tang P, Yu JS, Liao WC, Chiang KW, Rodriguez H, Myers JN., Chang KP, Chang YS (2017, Sep). APOBEC3A is an oral cancer prognostic biomarker in Taiwanese carriers of an APOBEC deletion polymorphism. <i>Nature Communication</i>, 8 (1):465.. MOST 103-2632-B-182-001. <span style="font-family:標楷體">本人為第一作者</span>. (SCI)</span></span></span></span></span></span></li>
<li style="text-align:justify"><span style="font-size:12pt"><span style="text-justify:inter-ideograph"><span style="tab-stops:list 0cm"><span style="punctuation-wrap:simple"><span style="text-autospace:ideograph-numeric"><span style="font-family:&quot;Times New Roman&quot;,serif"> Yang CC, Chen YT, Chang YF, <b><u>Liu H</u></b>, Kuo YP, Shih CT, Liao WC, Chen HW, Tsai WS, Tan, BC (2017, May). ADAR1 mediated 3&rsquo; UTR editing and expression control of anti-apoptosis genes fine-tunes cellular apoptosis response. <i>Cell Death and Disease</i>, 8(5):e2833. MOST 105-2320-B-182-017. (SCI).</span></span></span></span></span></span></li>
<li><span style="font-size:12pt"><span style="tab-stops:list 0cm"><span style="font-family:&quot;Times New Roman&quot;,serif"> Chen H, Hsiao YC, Chiang SF, Wu CC, Lin YT, <b><u>Liu H</u></b>, Zhao H, Chen JS, Chang YS, Yu JS. (2016, Aug). Quantitative analysis of wild-type and V600E mutant BRAF proteins in colorectal carcinoma using immunoenrichment and targeted mass spectrometry. <i>Analytica Chimica Acta</i>, 933:144-55. (SCI).</span></span></span></li>
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